The modal properties of large-mode-area microstructured optical fiber with two-ring holes are analyzed. By using the multipole method and finite element method, the influence of inner and out hole sizes on the fundamental mode and higher-order mode losses of the fiber are numerically calculated and analyzed. In addition, a large-mode area microstructured optical fiber is designed with high loss ratio of higher-order mode and fundmental mode as well as allowing for bending at a moderate radius. For the fiber with the inner ring of hole diameters of 34 μm and the outer ring of hole diameters of 24 μm, the fundamental mode loss is 0.000 17 dB/m, whereas the high order mode loss is 1.39 dB/m. The mode area of the fundamental mode is 2 150.9 μm2, and the bending loss at the bending radius of 1.2 m is 0.106 dB/m.