The incorporation of tuff powder into cement-based materials as mineral admixtures can reduce cement production and greenhouse gas emissions such as CO2, as well as utilize industrial solid waste. This review represented the mechanism of tuff powder in cement-based materials, and summarized the influence of tuff powder incorporation on the setting time, workability, mechanical properties and durability of cement-based materials. Some aspects for the preparation and use of tuff powder were given, and some problems for the effect of tuff powder on the properties of cement-based materials were proposed. In addition, some aspects for future studies on the properties of cement-based materials incorporating tuff powder were also discussed.