Data collected by CCD camera is a function of wavelength in Spectral-Domain Optical Coherence Tomography(SDOCT) system.By consideration of a wavelength-depended response characteristics of CCD and the Fourier transform relationship between time(distance) and frequency(wave-number),the CCD data must be responsivity-compensated and resampled by linear interpolation in frequency space.Based on the above analysis,the CCD response compensation method and the linear interpolation arithmetic were suggested and tested by the sample imaging.Results show that signal-to-noise ratio(SNR) increases a 30% in proposed method and arithmetic mentioned above,and the OCT image quality is greatly improved.