In the present paper, the methods of spin-coating and physical vapor deposition (PVD) were researched to prepare the coronene film for UV-CCD, and their properties were characterized and compared with each other. The results of the experiment show that the process of spin-coating is relatively simple, which takes advantage of materials and retains the inherent crystal structure of coronene. However, the roughness of the film is a little more than that of PVD method; the film prepared by PVD method can absorb ultraviolet more effectively and then emits fluorescence with more intensity. Compared with the method of spin-coating, the surface of PVD film is more smoothly, and the process of thermal evaporation changes the crystal structure of coronene and forms another new crystalline state according to the XRD graph. While the whole process of PVD is more complex and it needs larger cost of production than spin-coating method. Besides, the comparison research work provided theoretical direction for preparing the photoluminescence down-conversion film under different requirements, such as fluorescence intensity, surface roughness and cost of production.