Optoelectronics Letters, Volume. 8, Issue 4, 314(2012)
Label-free quantitative detection using porous silicon as optical biosensor
The single-layer porous silicon is prepared by electrochemistry etching method, which is used as an immunosensor for determining recombinant mouse zona pellucida 3 fusion protein (r-mZP3) by Raman spectroscopy analysis at room temperature. The molecule binding increases the effective optical thickness (EOT), and thus the Raman spectrum intensity decreases. The concentration and variation of Raman intensity show a good linear quantitative relation. The excellent sensing performance could open the way to a new family of optical sensors for biological standardization.
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ZHONG Fu-ru, MA Xiao-lin, Lü Xiao-yi, JIA Zhen-hong. Label-free quantitative detection using porous silicon as optical biosensor[J]. Optoelectronics Letters, 2012, 8(4): 314
Received: Mar. 20, 2012
Accepted: --
Published Online: Jul. 12, 2017
The Author Email: Zhen-hong JIA (jzhh@xju.edu.cn)