Using C16H36O4Ti, H2O, CH3COOH, C2H6O, La2O3 and CeO2 as raw materials.The nanostructure TiO2 and rare earth element (La, Ce) doped TiO2 composite were prepared by sol-gel method. The Performance and property of samples were studied by X-ray diffractometer, scanning electron microscope, ICP-OES, UV-Vis spectrometer and Medium diffusion. The result of experiment show that the experiment prepared to anatase crystal type of TiO2 powder and La/TiO2 powder, because cerium oxide slightly soluble in sour, doesn’t dissolve in solution.Ce is basically not mixed into titanium dioxide. The powder main of anatase type TiO2 and the compound of cerium oxides, no effect on the performance of TiO2.In the La/TiO powder has 8.24% La element. The 300 min La/TiO2 photocatalytic rhodamine B solution’s decolourization ratio increase to 91.2%, it has good inhibitory effect on staphylococcus aureus.