Journal of Innovative Optical Health Sciences, Volume. 14, Issue 2, 2150004(2021)

Corneal damage effects induced by infrared optical parametric oscillator radiation at 3743 nm

Luguang Jiao*... Chao Wang, Kaizeng Zhang, Jiarui Wang and Zaifu Yang |Show fewer author(s)
Author Affiliations
  • Beijing Institute of Radiation Medicine, Beijing 100850, P. R. China
  • show less

    The main aim of this paper is to investigate the corneal damage effects induced by mid-infrared optical parametric oscillator (OPO) radiation. Experiments were performed to determine the corneal damage thresholds of New Zealand white rabbit at the wavelength of 3743 nm for exposure durations of 0.1 s, 1.0 s and 10.0 s. Through slit-lamp biomicroscope and histopathology, corneal injury characteristics were revealed. The damage thresholds were 3.73 J/cm2, 7.91 J/cm2 and 31.1 J/cm2, respectively, for exposure durations of 0.1 s, 1.0 s and 10.0 s. The damage data was correlated by an empirical equation: Radiant exposure at the threshold = 9.72 × exposure duration,0.46 where the units of radiant exposure and exposure duration were J/cm2 and second. At near-threshold level, corneal injuries at 1 h post-exposure mainly involved the epithelium, and the epithelium damages repaired at 24-h post-exposure. There are sufficient safety margins between the damage thresholds and the maximum permitted exposures from current international laser safety standard IEC 60825-1.

    Tools

    Get Citation

    Copy Citation Text

    Luguang Jiao, Chao Wang, Kaizeng Zhang, Jiarui Wang, Zaifu Yang. Corneal damage effects induced by infrared optical parametric oscillator radiation at 3743 nm[J]. Journal of Innovative Optical Health Sciences, 2021, 14(2): 2150004

    Download Citation

    EndNote(RIS)BibTexPlain Text
    Save article for my favorites
    Paper Information

    Received: Aug. 30, 2020

    Accepted: Nov. 23, 2020

    Published Online: Apr. 7, 2021

    The Author Email: Jiao Luguang (jiaoluguang001@163.com)

    DOI:10.1142/s1793545821500048

    Topics