Acta Optica Sinica, Volume. 36, Issue 7, 717001(2016)

Fast Reconstruction in Fluorescence Molecular Tomography Based on Locality Preserving Projections

Zhang Xu*, Yi Huangjian, Hou Yuqing, Zhang Haibo, and He Xiaowei
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    Image reconstruction with large scale of fluorescence molecular tomography (FMT) data needs a large amount of computational memory and time. In order to reduce the ill-posedness of FMT and speed up the reconstruction,an accelerated reconstruction method for FMT based on locality preserving projections (LPP) and sparse regularization algorithm is presented, combining with the manifold learning and compressive sensing theory. The original fluorescent multi-projection data is reconstructed. Simulation experiment of non-homogeneous cylinder single and double goal and real experiment are performed to evaluate the reconstruction effect and time of the proposed method respectively. Experimental results demonstrate that the proposed method can ensure the accuracy and resolution of the FMT reconstruction image and reduce the reconstruction time greatly.

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    Zhang Xu, Yi Huangjian, Hou Yuqing, Zhang Haibo, He Xiaowei. Fast Reconstruction in Fluorescence Molecular Tomography Based on Locality Preserving Projections[J]. Acta Optica Sinica, 2016, 36(7): 717001

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    Paper Information

    Category: Medical Optics and Biotechnology

    Received: Jan. 18, 2016

    Accepted: --

    Published Online: Jul. 8, 2016

    The Author Email: Xu Zhang (zhangxuaxc@stumail.nwu.edu.cn)

    DOI:10.3788/aos201636.0717001

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