Journal of Innovative Optical Health Sciences, Volume. 17, Issue 1, 2350016(2024)
Intravascular photoacoustic and optical coherence tomography imaging dual-mode system for detecting spontaneous coronary artery dissection: A feasibility study
In this work, we present an intravascular dual-mode endoscopic system capable of both intravascular photoacoustic imaging (IVPAI) and intravascular optical coherence tomography (IVOCT) for recognizing spontaneous coronary artery dissection (SCAD) phantoms. IVPAI provides high-resolution and high-penetration images of intramural hematoma (IMH) at different depths, so it is especially useful for imaging deep blood clots associated with imaging phantoms. IVOCT can readily visualize the double-lumen morphology of blood vessel walls to identify intimal tears. We also demonstrate the capability of this dual-mode endoscopic system using mimicking phantoms and biological samples of blood clots in ex vivo porcine arteries. The results of the experiments indicate that the combined IVPAI and IVOCT technique has the potential to provide a more accurate SCAD assessment method for clinical applications.
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Yongwei Wang, Yuyang Wan, Zhongjiang Chen. Intravascular photoacoustic and optical coherence tomography imaging dual-mode system for detecting spontaneous coronary artery dissection: A feasibility study[J]. Journal of Innovative Optical Health Sciences, 2024, 17(1): 2350016
Category: Research Articles
Received: Mar. 7, 2023
Accepted: May. 17, 2023
Published Online: Feb. 28, 2024
The Author Email: Chen Zhongjiang (zjchen@fjmu.edu.cn)