The proposed method also has disadvantages: first, the period of the fringe/lattice patterns can not be varied digitally like what in SLM/DMD-based SIM. Second, the resolution enhancement achieved with this method is less isotropic than the standard 3-angle 2-beam SIM. Both drawbacks can be solved by using a specially-designed Diffractive Optical Element (DOE) instead of the 2D grating used in the current technique and by recording more raw images under different phase-shift combinations. Once using a 2D amplitude grating that has the same transmittance for different illumination wavelengths, the large-field SIM also allows multi-color SIM imaging. We can envisage that the proposed method can be applied to many fields, including biomedical, industrial, and chemical fields.