Iron oxide dry desulphurization is an effective method for H2S removal. In this paper, three limonite materials from Yeshan, Xinqiao and Shao jilao iron mines were selected as desulfurizers for hydrogen sulfide removal. The effects of calcination temperature and reaction temperature on the desulfurization performance of limonite were investigated at medium-high temperatures, and a desulfurization cycle regeneration experiment was conducted. The removal mechanism of hydrogen sulfide was analyzed by X-ray diffraction, scanning electron microscopy and X-ray photoelectron spectroscopy. The results show that SJL-300 as an effective desulfurizer has a total desulfurization capacity of 1 525.7mg/g after seven cycles. In the evolution process of the reaction between limonite and hydrogen sulfide, pyrite and pyrrhotite are the desulfurization products at 300-400 ℃, while only pyrrhotite appears at > 500 ℃.