In recent years, Chinese researchers have done a myriad of representative works in the field of rational design and construction, surface functional engineering, optimization and mechanism exploration of physicochemical properties, and biomedical applications of materdicine and medmaterials. To showcase the state-of-the-art research achievements of Chinese scientists in the field of materdicine and stimulate the interest of all walks of life in materdicine and medmaterial, the Editorial Board of the Journal of Inorganic Materials herein invited Prof. CHEN Yu from Shanghai University as guest editor to compile this Special Issue themed “Medmaterials”. This issue contains the latest reviews and research papers related to medical materials, including piezoelectric semiconductor nanomaterials, group VA single- element two-dimensional materials, bioactive ceramics, metal alloys, and silica-based micelles. It is hoped that this special issue will promote the cooperation of researchers and scientists from many fields with different disciplinary backgrounds, and jointly promote the development of the field of materdicine and medmaterial, so as to revolutionize the diagnosis and treatment of various diseases in clinical medicine for the benefit of human health.