The five novel N-heterocyclic carbine imidazole hexafluorophosphate (5a-5e) were synthesized by choosing quinaldine as bridging group.The structures were characterized by 1H NMR and 13C NMR, and crystal structures of 5b, 5c and 5e were determined by X-ray single crystal diffraction. The single crystal X-ray diffraction analysis reveals that crystals of 5b and 5c both belong to P1- space group with the triclinic system, crystal of 5e belongs to Cc space group with monoclinic system, the cell parameters of 5b is a=6.945 1(10)nm, b=12.016 6(18) nm, c=14.791(2) nm, α=91.997(11)°, β=95.340(12)°, γ=105.845(8)°, the cell parameters of 5c is a=9.975(3) nm, b=11.056(4)nm, c=12.382(4) nm, α=99.010(4)°, β=103.527(3)°, γ=112.734(3)°. The cell parameters of 5e is: a=18.058 9(18) nm, b=12.510 0(9) nm, c=13.365 9(12) nm, α=90.00°, β=124.522(7)°, γ=90.00°. The results of bacteriostatic experiments reveal that 5a-5e could show certain bacteriostatic effect on S. aureus and E.coli.