Deicing salt with chlorine salt as main component can cause salt-frost damage to concrete, while Ca-Al hydrotalcite (CAHL) can adsorb and solidify chloride ion. In order to study the influence of CAHL on the salt-frost resistance of concrete, CAHL with the mass fraction of 0%, 0.5%, 1.0%, 1.5% and 2.0% of cementing material was added into C30 concrete, and the influence of different CAHL content on compressive strength, electric flux, salt-frost spalling mass and free chloride ion concentration of concrete was tested. The results show that when the content of CAHL is ≤1.5%, the compressive strength of concrete increases gradually with the increase of CAHL content, while the electric flux decreases gradually, indicating that CAHL can improve the compactness of concrete better under the appropriate content of CAHL. The diffraction peak of Friedel’s salt increases gradually with the increase of CAHL content, indicating that CAHL can solidify chloride ion well. By improving the compactness of concrete and solidifying chloride ion, the content of free chloride ion in concrete under salt-frost condition is effectively reduced after adding CAHL. Compared with the blank sample, the mass loss of concrete with CAHL content of 1.5% decreases by 22.9% after 28 times single-sided salt-frost spalling.