Anatase TiO2 spheres with algae spherical shape were synthesized using Na salt and K salt by normal pressure hydrolysis-ion exchange method. The surface of the material is covered with ultra-fine nano-TiO2 whiskers, forming three-dimensional, interconnected, nanopore anatase structure. The crystal structure and morphology were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM), and the electrochemical performance of lithium storage was tested. The material exhibits excellent electrochemical performance. At a current density of 100 mA · g-1, the first specific discharge capacities of samples synthesized from Na salt and K salt methods are 347 mAh·g-1 and 242 mAh·g-1, respectively. The TiO2 sample prepared by Na salt has better rate performance, it has a high specific capacity of 168 mAh·g-1 at a current density of 2 000 mA · g-1, and shows good cycling performance, it still remains at 153 mAh·g-1 after 20 cycles.