Cardiovascular disease and coronary artery stenosis are closely related.Detection and quantification of coronary artery stenosis is important for cardiovascular disease prevention,detection and diagnosis.As the rapid growth of medical imaging and image processing techniques,automatic and semi-automatic stenosis detection,as well as quantification,has become an important development direction in the field of medical image processing.The related technologies include automatic coronary artery tree labeling on computed tomography angiography (CTA),vessel tractography,and robust kernel regression,etc.The latest advance in coronary artery stenosis detection and quantification in the recent years is reviewed,the technological process of stenosis detection is summarized,and the tendency and application prospect in the future is discussed.