It’s an important work to detect and locate targets in image. A new method,named Data Regrouping (DRG) algorithm,is proposed. This approach scans the image only once to record data related to targets,and transforms image process problem to data structure problem,thus complexity is reduced. The DRG method doesn’t need overlaborate labeling and has nothing with repetitiveness. Using the infrared images of ground gathered by the sensor of our airborne testing system for heavy-weapon range test,we apply DRG algorithm to extract infrared small targets and achieve the goal of detecting and locating ground control points in real time. The experiment result shows that our method is accurate,reliable,and has great ability of anti-jamming and anti-noise.