Journal of Innovative Optical Health Sciences, Volume. 7, Issue 2, 1450033(2014)
Early identification of acute hypoxia based on brain NADH fluorescence and cerebral blood flow
Hypoxia is closely related to many diseases and often leads to death. Early detection and identification of the hypoxia causes may help to promptly determine the right rescue plan and reduce the mortality. We proposed a new multiparametric monitoring method employing mitochondrial reduced nicotinamide adenine dinucleotide (NADH) fluorescence, regional reflectance, regional cerebral blood flow (CBF), electrocardiography (ECG), and respiration under six kinds of acute hypoxia in four categories to investigate a correlation between the parameter variances and the hypoxia causes. The variation patterns of the parameters were discussed, and the combination of NADH and CBF may contribute to the identification of the causes of hypoxia.
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Hua Shi, Nannan Sun, Avraham Mayevsky, Zhihong Zhang, Qingming Luo. Early identification of acute hypoxia based on brain NADH fluorescence and cerebral blood flow[J]. Journal of Innovative Optical Health Sciences, 2014, 7(2): 1450033
Received: Jan. 25, 2014
Accepted: Feb. 20, 2014
Published Online: Jan. 10, 2019
The Author Email: Luo Qingming (qluo@mail.hust.edu.cn)