Journal of Innovative Optical Health Sciences, Volume. 15, Issue 3, 2250019(2022)

Automated retinal layer segmentation in optical coherence tomography images with intraretinal fluid

[in Chinese]1... [in Chinese]1, [in Chinese]1, [in Chinese]2,3, [in Chinese]2,3,4, [in Chinese]2,3, [in Chinese]2,3, [in Chinese]2,3, [in Chinese]5, [in Chinese]2,3,4,*, and [in Chinese]2,6,78 |Show fewer author(s)
Author Affiliations
  • 1School of Mechatronic Engineering and Automation, Foshan University, Foshan, Guangdong 528000, P. R. China
  • 2School of Physics and Optoelectronic Engineering, Foshan University. Foshan, Guangdong 528000, P. R. China
  • 3Guangdong-Hong Kong-Macao Intelligent Micro-Nano, Optoelectronic Technology Joint Laboratory, Foshan University, Foshan, Guangdong 528000, P. R. China
  • 4Guangdong Provincial Key Laboratory of Animal Molecular Design and Precise Breeding, Foshan Guangdong 528000, P. R. China
  • 5Laboratory of Quantum Engineering and Quantum Material, School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou Guangdong 510006, P. R. China
  • 6Department of Biomedical Engineering, Peking University, Beijing 100081, P. R. China
  • 7Key Laboratory of Carcinogenesis and Translational Research, Cancer Hospital and Institute, Peking University, Beijing 100142, P. R. China
  • 8School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, P. R. China
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    We propose a novel retinal layer segmentation method to accurately segment 10 retinal layers in optical coherence tomography (OCT) images with intraretinal fluid. The method used a fan filter to enhance the linear information pertaining to retinal boundaries in an OCT image by reducing the effect of vessel shadows and fluid regions. A random forest classifier was employed to predict the location of the boundaries. Two novel methods of boundary redirection (SR) and similarity correction (SC) were combined to carry out boundary tracking and thereby accurately locate retinal layer boundaries. Experiments were performed on healthy controls and subjects with diabetic macular edema (DME). The proposed method required an average of 415 s for healthy controls and of 482 s for subjects with DME and achieved high accuracy for both groups of subjects. The proposed method requires a shorter running time than previous methods and also provides high accuracy. Thus, the proposed method may be a better choice for small training datasets.

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    [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese], [in Chinese]. Automated retinal layer segmentation in optical coherence tomography images with intraretinal fluid[J]. Journal of Innovative Optical Health Sciences, 2022, 15(3): 2250019

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    Paper Information

    Received: Oct. 31, 2021

    Accepted: Feb. 16, 2022

    Published Online: Aug. 26, 2022

    The Author Email: (yuanxiufeng138@163.com)

    DOI:10.1142/s1793545822500195

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