To non-dispersive infrared gas analysis, it was the most difficult challenge to maintain very low zero and temperature drift over long periods. Electronic and detector response drifts irremediably required some form of manual zeroing procedure. To solve zero and temperature drift, a multi-parameters model was developed, by which zero and temperature drifts were automatically corrected. These parameters include zero gas intensity, reference channels intensity, standard temperature, environment temperature, temperature drift coefficients etc. Trial results and in-situ applications showed that the monitoring precisions of the instrument were lesser than 5%F.S in different temperatures and for a long time. The average precision of monitoring carbon monoxide concentration increased respectively from 9.26% to 1.23%, and monitoring hydrocarbon concentration from 10.61% to 0.70% before and after compensated. The instrument required essentially no periodic calibration and have very low maintenance cost.