Considering the uneven illumination of Chang′E-3 pancam images sequences and the particularity of the lunar surface image, a new panoramic mosaics method based on speed up robust features (SURF) algorithm is put forward to achieve the panoramic mosaics of Chang′E-3 pancam images. The feature points of images are extracted using SURF algorithm, and euclidean distance of SURF descriptor is used as the measurement to obtain the corresponding image points. The transformation matrix are calculated and optimized between adjacent images by Levenberg-Marquardt algorithm. Fusion images can be achieved by using the fade in fade out method based on linear interpolation, realizing seamless mosaic of the lunar surface image. The results show that this method can achieve mosaic of Chang′E-3 pancam images in a rapid and accurate way, and the mosaic satisfy the demands of rover for selecting detect target and path planning.