A method for developing the virtual reality simulation system based on a Visual C++ and Multigen Vega is introduced. First, the 3D model with the texture is built by Greator software, and then the infrared texture and atmosphere conditions are modeled respectively by TMM and MOSART, finally IR image is simulated by Vega sensor model. The full design functions of IR visible simulation system are realized by using Vega API based on Visual C++ integrated development environment. The simulation procedures and simulation results are given, the simulation results prove that this method gets the ideal effects of simulation.