In view of the conflict between the real-time property and high speed digital image processing system, the real-time image processing system based on multi-DSP(digital signal processor TMS320C6416)and FPGA (field programmable gate array) is designed. The selection of hardware source, basic components, working principle, power supply design, DSP boot loading principle and software design of the system are introduced. The experimental result indicates that the system meets the requirement of real time high speed digital image processing by 640×512 pixel, 14-bit, 25 frame/s digital image. At the same time, the higher speed DSP (e.g. TMS320C6455 series) can realize the more complex real-time image processing.