The sulfur dioxide (SO2) concentration during 2005～2012 over China was monitored from the planetary boundary layer (PBL) SO2 column density retrieved from Aura Ozone Monitoring Instrument (OMI) data and land use types of China from MODIS. Spatial analysis was adopted to analyze PBL SO2 column density’s spatial characteristics with time and land use type respectively over China. From the perspective of spatiotemporal variations, the result shows that the high SO2 density in China is mainly concentrated in the area of Urumqi, Beijing-Tianjin-Hebei, Yangtze River Delta, Sichuan Basin and Pearl River Delta region. Besides, the SO2 value in northern China is high in winter and low in summer, and has a rising trend in recent years. The SO2 value in South China is low in winter and high in summer, and the peak value has decreased during 2005～2012. In terms of land use, the high value of SO2 was found in urban and crop land, while the low value of SO2 was found in forest, lawn and bare land. Those results reflect that human activities play a key role in the distribution and variation of PBL SO2.