The large size direct coupling technology was studied by coupling a 40 mm diameter image intensifier with a full-frame CMOS. To solve the problems of large-size ICCD/ICMOS made by lens coupling, such as large volume, large light energy loss, and large number of moiré fringes in optical cone coupling devices, a direct coupling process is proposed to make ICCD/ICMOS. The large-size ICMOS developed in this study can obtain more information in the field of view. The resolution of the entire device is up to 3600.1800, the picture is clear, there is no obvious moiré fringe, and the structure is compact. The entire device has the size of a handheld digital camera and has strong concealability, which is conducive to obtaining target information more accurately and quickly in a complex environment.