This paper mainly studies the decision-making problem of Airborne Warning and Control System(AWACS) when guiding modern fighters to attack multiple targetsanalyzes the advantages of decision-making and guidance by using AWACS, and gives a decision-making route and solution. Based on the threat evaluation and value evaluation to the target , the first target to be attacked and the weights of the rests are determined. Then, the objective function of the occupation decision is constructed to solve the optimal attack route.The simulation result shows that the proposed method can give full play to the intelligence advantage of AWACS, guide the fighter to approach the targets stealthily, and capture and strike the scattered targets in dominant positions.