At present, various chaos-based image encryption algorithms have been designed and developed for different scenarios, but there are still shortcomings of some of the image encryption algorithms.Therefore, relevant experts and scholars continue to study new image encryption methods and improve traditional encryption algorithms.In order to overcome the obvious shortcomings of the current low-dimensional chaotic algorithm, this paper presents an image encryption algorithm based on the combination of CNN hyperchaotic sequence and S-box.Simulation experiments show that：1) The proposed algorithm can effectively resist the attack on the image in the form of plain text or cipher text, realize one-time one-encryption, and have a larger key space; and 2) This algorithm has excellent encryption effects with high speed and low complexity.