Based on image processing, the image non-uniformity testing method is proposed as the reference to determine whether the infrared imaging equipment in normal operation or not. The images from the standard infrared imaging equipment are taken as standard images. Under the same testing condition, the infrared imaging equipment to be tested is used to capture infrared images, the difference with the standard images is made, and the difference images are performed through binaryzation processing and the standard deviation of the equipment is deduced. According to Romanowski criterion, non-uniformity determination criterion of the infrared imaging equipment is established. The standard deviation of the equipment to be tested is used to determine whether the equipment has non-uniformity or not.