Acta Optica Sinica, Volume. 42, Issue 7, 0717001(2022)

Laparoscopic Laser Speckle Blood Flow Imaging Technology

Qiong Wu1,2, Wei Zhou1, Baoteng Xu1,3, Jialin Liu1、**, Xibin Yang1,3、*, Chi Wang2, and Daxi Xiong1
Author Affiliations
  • 1Suzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, Jiangsu 215163, China
  • 2School of Mechatronic Engineering and Automation, Shanghai University, Shanghai 200444, China
  • 3School of Biomedical Engineering, University of Science and Technology of China, Hefei, Anhui 230026, China
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    Laser speckle contrast imaging (LSCI) technology is widely used in tissue surface blood flow imaging with large field of view. When real-time in vivo monitoring of blood flow distribution and changes in deep tissue or lumen tissue is needed, the combination of LSCI and endoscopic imaging is an effective way to solve the problem of LSCI imaging depth. For this reason, a commercial laparoscopic LSCI imaging system is built to image microfluidic replicas and rabbit large intestine. The experimental results show that the system can correct the static scattering and eliminate the influence of system noise on speckle contrast, and the quantitative monitoring of blood flow can be realized by using the speckle contrast measurement under single exposure. The commercial laparoscopic LSCI imaging system will have important clinical application potential.

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    Qiong Wu, Wei Zhou, Baoteng Xu, Jialin Liu, Xibin Yang, Chi Wang, Daxi Xiong. Laparoscopic Laser Speckle Blood Flow Imaging Technology[J]. Acta Optica Sinica, 2022, 42(7): 0717001

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    Paper Information

    Category: Medical optics and biotechnology

    Received: Jun. 2, 2021

    Accepted: Sep. 22, 2021

    Published Online: Mar. 28, 2022

    The Author Email: Liu Jialin (liujl@sibet.ac.cn), Yang Xibin (yangxb@sibet.ac.cn)

    DOI:10.3788/AOS202242.0717001

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