Chinese Optics Letters, Volume. 8, Issue 1, 86(2010)
Detection system for singlet oxygen luminescence in photodynamic therapy
Singlet oxygen (<sup>1</sup>O<sub>2</sub>) is widely considered to play a major role in photodynamic therapy (PDT), and thus an increasing attention has been focused on the direct detection of <sup>1</sup>O<sub>2</sub> near-infrared luminescence around 1270 nm for PDT dosimetry. A new sensitive detection system is developed to directly measure the temporal and spectral resolved <sup>1</sup>O<sub>2</sub> luminescence spectra. The triplet state and <sup>1</sup>O<sub>2</sub> lifetimes of Rose Bengal as a model photosensitizer in different solvents are determined, and the obtained results agree well with the published data. Our detection system has the potential application in <sup>1</sup>O<sub>2</sub> luminescence-based PDT dosimetry.
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Buhong Li, Huiyun Lin, Defu Chen, Min Wang, Shusen Xie. Detection system for singlet oxygen luminescence in photodynamic therapy[J]. Chinese Optics Letters, 2010, 8(1): 86
Received: Oct. 21, 2009
Accepted: --
Published Online: Mar. 1, 2010
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