The quantum effect of mesoscopic inductance-capacitance coupled circuit with mutual inductance was investigated by canonical transformation and unitary transformation. The mesoscopic inductance-capacitance coupled circuit was compared with several coupling circuits. It is found that it is convenient to control the quantum fluctuations and squeezed effect by adjusting mutual inductance coupling coefficient in mutual inductance circuit with coupling capacitance. Uncertainty relations of charges and conjugate currents are related to canonical transformation parameter φ and uncertainty relations parameter ξ. When ξ→1 or φ→nπ/2, (n = 0,1,2,…), the uncertainty relations approach minimum value h/2.