A comprehensive experiment on the cerium-vanadium hollow nanopillar arrays (CeV-HNA) for electrocatalytic oxygen evolution reaction (OER) is designed based on the concept of research-oriented teaching and the scientific research achievements of the teacher. Vanadium based metal organic framework nanopillar arrays were firstly prepared on foam nickel by in-situ growth, and then Ce salt etching and high-temperature calcination were executed to construct CeV-HNA, achieving a freestanding catalyst. Furtherly, scanning electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy and other analytical testing methods were employed to characterize the structure of the prepared catalyst. Finally, its OER performance was investigated. This teaching experiment is comprehensive, cutting-edge and interesting, which contributes to exercise students’ comprehensive practical abilities, stimulate their research enthusiasm and cultivate their innovation ability.