We investigate the spatial coherence of the light generated from high-power multi-chip red LEDs by using the van Cittert- Zernike theorem. It is theoretically demonstrated that the light generated from multi-chip LEDs evolves into partially coherent light after propagation, and the spatial coherence is increased with the increase of propagation distance. Moreover, the spatial coherence of the light is found to be closely related to the chip distribution of multi-chip LEDs. The distribution of the spatial coherence of the light is experimentally examined by Young’s double-slit interference. It is found that the experimental results are consistent with the theoretical ones.