Spectroscopy and Spectral Analysis, Volume. 36, Issue 4, 1109(2016)
Spectroscopic Studies on the Interaction of Human Serum Albumin and Water-Soluble Carboxyl Carbon Nanotubes
The interaction between nanomaterials and biological macromolecules (including protein) is the important basis of biological safety assessments of nanomaterials. In this paper, the fluorescence spectroscopy, synchronous fluorescence spectroscopy and circular dichroism spectroscopy) were used to analyze the interaction between four water-soluble carboxyl carbon nanotubes (long-SWCNTs-COOH, short-SWCNTs-COOH, DWCNTs-COOH and MWCNTs-COOH) and human serum albumin. Results showed that the four water-soluble carboxylated carbon nanotubes could quench the intrinsic fluorescence of human serum albumin at different extents. Under the same concentration, the quenching ability of four carboxylated carbon nanotubes were in the order of DWCNTs-COOH
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WU Shu-rong, LIU Ying, LIU Shu-fang. Spectroscopic Studies on the Interaction of Human Serum Albumin and Water-Soluble Carboxyl Carbon Nanotubes[J]. Spectroscopy and Spectral Analysis, 2016, 36(4): 1109
Received: Dec. 27, 2014
Accepted: --
Published Online: Dec. 20, 2016
The Author Email: Shu-rong WU (wushurong2009@163.com)