Journal of Inorganic Materials, Volume. 36, Issue 11, 1208(2021)

Carbon Spheres for Photothermal Therapy of Tumor Cells: Rapid Preparation and High Photothermal Effect

Chengxiong WEI... Xin JIN, Peinan YIN, Chengwei WU and Wei ZHANG* |Show fewer author(s)
Author Affiliations
  • Laboratory of Biology and Nanomechanics, Department of Engineering Mechanics, State Key Laboratory of Structural Analysis for Industrial Equipment, Dalian University of Technology, Dalian 116024, China
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    Photothermal therapy is a new non-invasive treatment method, which can make up for the deficiency of traditional tumor therapy. As an efficient photothermal agent, carbon nanomaterials show great potential in the photothermal therapy of tumor. In this study, a rapid polymerization of pyrogallic acid and formaldehyde was induced by ultrasound-assisted method. Carbon spheres with good biocompatibility and high photothermal conversion efficiency were quickly prepared by subsequent calcination treatment. The prepared carbon spheres are highly monodisperse and uniform in size. Under 808 nm near-infrared light irradiation, they exhibit good photothermal effect and photothermal stability with photothermal conversion efficiency up to 41.4%. Cell experiments show that carbon spheres have no obvious cytotoxicity, and can effectively kill the tumor cells under near-infrared light irradiation. This work is expected to construct efficient photothermal carbon spheres for photothermal therapy of tumor.

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    Chengxiong WEI, Xin JIN, Peinan YIN, Chengwei WU, Wei ZHANG. Carbon Spheres for Photothermal Therapy of Tumor Cells: Rapid Preparation and High Photothermal Effect[J]. Journal of Inorganic Materials, 2021, 36(11): 1208

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    Paper Information

    Category: RESEARCH ARTICLE

    Received: Mar. 1, 2021

    Accepted: --

    Published Online: Dec. 20, 2021

    The Author Email: ZHANG Wei (wei.zhang@dlut.edu.cn)

    DOI:10.15541/jim20210124

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