Chemical strengthened lithium aluminum silicon (LAS) glass undergoes heat treatment steps such as curved surface forming and ion exchange during further processing, which affects its compressive stress distribution and structural strength. In this experiment, the influence of heat treatment process at 420~640 ℃ on the properties of LAS glass was investigated and characterized by single rod static pressure test, drop resistance test and Raman spectroscopy. The results show that the mechanical properties of LAS glass can be enhanced by heat treatment at the temperature range from the strain point 60 ℃ blow to the strain point, which is characterized by the increase of density, the increase of unit exchange stress, the decrease of compressive stress depth and the increase of static compressive strength of single rod. Raman spectrum analysis shows that the structure of the glass network is changed during the heat treatment process in this temperature range. The length of the silicon oxygen and aluminum oxygen tetrahedral bonds of the six-membered rings in the glass becomes shorter, and the structure of the linked network becomes denser. However, when the heat treatment temperature exceeds the strain point, the bridging oxygen between the silico-oxygen tetrahedrons begins to break, forming a relatively loose structure, and the mechanical properties decline.