In accordance with the need of a larer ground-based high resolution imaging telescope for adaptive optical wave-front processing,an Adaptive Optical(AO) wave-front processing system with larger calculation and thousands of units was designed based on the Field Programming Gate Array(FPGA) and its operation scheme,implement processing and tested results were given. At the software,the FGPA was used to configure and control data and to realize the conversion and transmission of multi-channel D/A data synchronously. Meanwhile,the FPGA was taken as a key element to preprocess the image and calculate the wave-front gradient of a sub-aperture.With satisfied wave-front processing precisions,it shortens wave-front processing delay and improves the ability of wave-front processing. Results demonstrate that the system can achieve the wave-front processing in 2 000 frame/s. At the hardware,this system combined the wave-front processing host board and wave-front processing sub board to improve the output ability of the system. As each wave-front processing sub board can promote the output of 120 road and the maximum expansion capacity of the main board is 10,the system can reach the momentum of the output in 1 200 road.