Laser-induced anti-Stokes fluorescent cooling is a brand-new conception in recent years. Compared with conventional cryocoolers, the crycooler based on anti-Stokes fluorescence cooling has the advantage of lifetime, vibration, size, weight, electromagnetic radiation, which possess enough adaptability to the tough space environment in practical space application. Anti-Stokes fluorescence cooling may be widely used in cooling infrared sensors and space remote sensing.