To deal with the threaten of new type radio fuze, we focus research on the interference mechanism of ultra wideband (UWB) radio fuze which is a new type radio fuze. In this paper, the response mechanism of the UWB fuze sensitive waveform is revealed, the response characteristic of fuze under periodic modulation jamming signal is deduced theoretically, and the correlator response characteristic of fuze under the interference of noise, sinusoidal amplitude modulation, and sinusoidal frequency modulation signal, is calculated and simulated. Based on the signal-interference-ratio gain, through theoretical calculation, simulation analysis and experimental verification, it is concluded that the AM sweep jamming is the more effective than the FM sweep jamming in the periodic modulation interference.