A field calibration campaign of ZY-3 multispectral sensor (MUS) was performed by the China Center for Resources Satellite Data and Application at the Dunhuang site. The reflectance-based method with two-point sites was used to obtain MUS absolute calibration coefficients in 2013. Compared to the calibration results in 2012, the calibration coefficients in 2013 changed by about 1%～8.5% in different bands. The results were also validated by intercalibration method using the Landsat 8 Operational Land Imager (OLI) data. It shows largely good consistency between field calibration and intercalibration. It was concluded that the absolute calibration coefficients were highly reliable.