A kinds of communication control board based on PCI bus is designed for improving the safety and stabilization of a photo-electrical detecting system.Firstly, the hardware design parts including the Field Programmable Gate Array(FPGA) circuit, PCI9054 design and other function modules are introduced and the PCI local bus control and the PCI system designed with the PCI9054 are studied.Then, other function modules used in the photo-electrical detecting system are shown.After finishing the design work, the communication control board is tested.Tested results indicate that the transmission velocity of PCI bus achieves 26.3 MByte/s, the least time unit is 1 ms with the accuracy of ±0.1 ms and the communication rate by eight series RS-422 is 230.4 kbit/s at the same time.The communication control board finished has been used in some important projects and has done well with high safety and stabilization under the complex environment.