In order to suppress the electromagnetic interference of a high-power TEA CO2 laser for the other electronic equipment, the near-field electromagnetic radiation characteristics of the laser were measured and analyzed, and an electromagnetic shielding cabin was designed and validated. According to the work principle of high-power TEA CO2 laser, the main electromagnetic radiation sources of the laser in working process were analyzed, then it points out that the main part of electromagnetic radiation tests is the spark switch, main circuit and the part of light out by combing of laser electromagnetic radiation theory and the actual structure. After analysis of test results, the main frequencies of laser radiation in different directions were obtained. Based on the above, the shielding cabin was designed, and its shielding effectiveness was verified near the cabin's door. The results show that the electromagnetic radiation of the high-power TEA CO2 laser is magnetic field source in the near-field zone, and the shielding efficiency is 40 dB for the whole frequencies and more than 60 dB for some special frequencies.