In order to effectively combat the laser guided weapons and improve the survivability of vehicle-mounted weapon systems on the battlefield, we proposed a laser induced bias interference countermeasures technology for vehicle-mounted active defense systems. According to the incoming threat information and characteristics of semi-active guided weapon systems, we discussed the feasibility of laser induced interference technique .Moreover we recorded the trajectory of the tracking system from tracking and identifying the target to starting the interference system by experimental device with synchronous forward interference mode. It is verified that the system can implement interference antagonism within 7 s and reach active protection ability.