The traditional index designed to evaluate infrared anti-jamming ability is relatively simpleand is mostly determined by the comprehensive anti-jamming probability. To solve this problem, we establishan anti-jamming performance evaluation index system including three levels of missiles, guidance systems, and seekers; construct the anti-jamming performance evaluation function; decompose anti-jamming performance evaluation indexes; and improve the anti-jamming performance of the guidance system and seeker. The evaluation ability of the system improves the ability touse the evaluation results of the seeker and guidance system to predict the anti-jamming performance of the guidance system.