A sixth-order Chebyshev active analog bandpass filter is designed for the characteristics and extraction requirements of the quartz tuning fork resonance signal in the quartz enhanced photoacoustic detection system. The actual circuit design is completed according to the Chebyshev filter theory and the Sallen-Key topology structure model, and the performance of the filter is verified through a quartz tuning fork resonance characteristic test experiment. The experimental results show that this filter can filter and de-noise the quartz tuning fork photoacoustic signal without distortion amplification. The specifications of the filter are that the passband is 935 Hz, ripple is 0.8 dB, out-of-band attenuation is 51 dB, and Q value is 35.09, which can effectively suppress ambient noise and can be used for processing photoacoustic front-end signals in the field of quartz enhanced photoacoustic spectrum detection.