Breathing, heart rate and snoring can reflect a lot of information of human body during sleep. In this paper, the polyvinylidene fluoride (PVDF) is used as a sensitive unit to monitor the signals of respiration, pulse and snoring. According to the characteristics of the sensor, the charge amplifier circuit, the notch circuit and the voltage amplifier circuit are designed. The hardware circuit is powered by the polymer lithium battery. According to the characteristics of polymer battery, charging circuit, protection circuit and discharge circuit are designed for the battery. The whole hardware circuit is integrated on a PCB. At the same time, the APP based on Android device is designed to display the physiological signal data in real time in the form of visualization, and to store the signal data for a long time, so as to facilitate the analysis and diagnosis of sleep breathing diseases by doctors in the later stage. The purpose of this study is to monitor sleep physiological parameters accurately and improve the comfort of subjects.