Due to the characteristics of wide mid-infrared transmission range, high non-linear coefficients, and easily fiberized performance, chalcogenide glass has very important applications in mid-infrared photonic integration, optical fiber source, sensing, and other optical fields. In recent years, with further development of the infrared optics, some progresses have been made in the research of chalcogenide glasses and their optical fibers. From this point of view, the research progress of the fabrication of low-loss chalcogenide fiber, and its application fields including fiber devices (couplers, combiners, bundles,and fiber gratings), fiber-based light sources, and optical fiber sensing at home and abroad are summarized in this review. Besides, some existing problems are analyzed and the future development direction is prospected.