To effectively realize the camera calibration on a position topography measurement, a multi-camera parallel calibration method is proposed based on a camera intrinsic parameter model. According to an active vision theory, four cameras are installed at four linear independence positions on a measuring support, and a parallel device is applied to drive these cameras for shooting at the same time, so as to accomplish the shooting effect of three linear independence translations. The calibration experiments of position topography measurement are designed based on this calibration method, the experiments show that the relative error of the scale factor ratio in two directions is less than 3.87%, the absolute error of central point a coordinate is less than 4 pixels,and the variation range of distortion factor is in 3 times. This method is suitable for position topography measurement for its convenient and fast calibration.