One of the major limitations of optical phase conjugation (OPC) for dispersion and nonlinearity compensation in optical fiber communication systems is that the power profile along the communication links should be symmetrical with respect to the optical phase conjugator. However, such a power profile is difficult to be realized in practical systems in which the communication link is composed of uniform fibers and periodic amplification using erbium-doped fiber amplifiers. It is numerically demonstrated that the difficulty can be overcome if the OPC is used in combination with pulse prechirp. Pulse prechirp can greatly reduce the interplay between the dispersion and nonlinearities and improve the communication performance. It is also shown that the effect of intra-pulse Raman scattering on the communication scheme is much smaller than that of third-order dispersion even for picosecond ultrashort pulses. Thus, more effective compensation can be achieved if spectral phase conjugation is used, instead of temporal phase conjugation for the scheme. The scheme is simple and effective, and it eliminates the need for special design or significant modification of the communication link.