Raman spectroscopy is a fast and nondestructive method, which is widely used in many fields. The peak and peak area method cannot meet the needs of product development. The paper took oxygen, nitrogen and carbon dioxide as the research, the quantitative analysis of peak value, peak area method, Rayleigh scattering normalization, a gas component normalization and the whole gas component normalization method were carried out. The four methods were compared in four terms: the influence of integration time, the stability and repeatability of quantitative detection, and whether they were restricted by 100% volume fraction. It is found that other methods can improve the repeatability and stability of measurement compared with peak and peak area method. Each of the four methods has advantages and disadvantages. In the process of product development, different quantitative calculation methods should be selected according to the requirements.